Maintenance Strategies for Homeless Youth’s Reductions in HIV Risk

Street Smart (SS) is an effective HIV preventive intervention for homeless youth selected by the CDC as part of Replicating Effective Programs. However, substantial relapse diminishes the program’s effects over two years. This study examines a computerized strategy for maintaining the efficacy of the SS intervention for 400 homeless youth in Los Angles, CA.

Project PROMOTE: Novel Strategies to Prevent Malaria and Improve HIV Outcomes in Africa — Data and Statistics Core

The overarching goal of this program project (P01) is to evaluate novel and strategic interventions to reduce the burden of malaria and improve HIV outcomes among children and pregnant women, the populations most affected by the overlap of these diseases. We hypothesize that treatment with HIV protease inhibitors (PIs) will lower the incidence of malaria and consequent morbidity in HIV+ children and pregnant women compared to those treated with standard antiretroviral treatment.

Risk Reduction for HIV Serodiscordant Couples Attempting Conception

The goal of this study is to develop a preliminary understanding of the social and cultural context in which HIV serodiscordant couples in Kenya are making the decision to become pregnant. The specific aims of this study are: To explore the motivations for conception, understanding the risk of HIV transmission, and the decisionmaking process of serodiscordant couples desiring pregnancy. To assess the acceptability of: Limiting unprotected intercourse to the fertile

Severity of Need: California Health Care Financing and Policy Research Initiative [summary]

The Ryan White HIV/AIDS Treatment Modernization Act (a reauthorization of the original Ryan White CARE Act) changed the formulas used to distribute funding to states and cities in the US. The case counts used to allocate the awards shifted from using only AIDS cases to using both HIV (non-AIDS) and AIDS cases.

Strengthening Capacity to Deliver HIV Research Counseling and Testing in International Biomedical Prevention and Treatment Trials

In this project we will develop, pilot and evaluate a curriculum for improving HIV research counseling and testing (HRCT) skills among staff working in international prevention and treatment clinical trials.

Structural Intervention to Improve HIV Test Counseling

This study has three components: Describe the strategies HIV rapid test counselors use to manage multiple roles during the test session. Develop a computer assisted survey that is self-administered by the client before they see the counselor (PalmPal). Enhance counselor training and supervision using time charts.

TRIP 2: Putting Community-Level HIV Prevention Research into Practice [summary]

=The Mpowerment Project is a model HIV prevention program that has been specifically designed to address the needs of young gay and bisexual men.

Using Technology to Streamline Client Data Collection and Improve HIV Test Counseling

This pilot study will determine the acceptability and translatability of PalmPal, an innovative structural intervention we designed to improve the process of HIV test counseling. PalmPal is a ten minute risk assessment questionnaire that is self administered by the client using a handheld computer just prior to the test session. The proposed study will recruit a representative sample of 40 test clients from three test clinics to conduct six focus groups.

Project REAC: Prevalence and Duration of False-Positive HIV Test Results in Acute Malaria

The HIV and malaria epidemics inflict the greatest harm in sub-Saharan Africa and overlap significantly. We have recently identified an interaction between acute malaria and false positive HIV EIA test results. This project will investigate this interaction in three of the most common rapid EIA HIV tests used in sub-Saharan Africa among a cohort of 450 HIV-uninfected children aged 2-17 years being followed longitudinally for malaria in Kampala, Uganda as part of a larger, parent study.

Exploring the Core of High-Risk Networks

Research shows that most men who use multiple types of public venues (bathhouses, sex clubs, parks, bars, etc.) to meet and engage other men reported high-risk behavior. These findings lead us to hypothesize that these high-risk men are a significant proportion of the core of high-risk networks; yet we know little about them. The purpose of this study is to narrow the focus of research to this core, to learn more about their intimate encounters.