PRC Products
Y2TEC
Y2TEC is a tech-based mental health intervention designed for youth living with HIV. Developed by researchers at CAPS/PRC UCSF, Y2TEC uses weekly video counseling and text messaging to support young adults (18-29) with mental health, substance use, and staying engaged in HIV care. Learn more about Y2TEC.
The Building Capacity to Implement Rapid Start ART to Improve Care Engagement Initiative
The Building Capacity to Implement Rapid Start ART to Improve Care Engagement initiative supported 14 sites across the U.S. in launching and expanding “Rapid Start” antiretroviral therapy (ART) services—helping people with HIV begin treatment as soon as possible after diagnosis or re-engagement in care. Funded by the Health Resources and Services Administration’s Ryan White HIV/AIDS Program (RWHAP) Part F – Special Projects of National Significance (SPNS), with additional support from the HHS Minority HIV/AIDS Fund, this project brought Rapid Start ART to a variety of settings, including RWHAP-funded clinics, Federally Qualified Health Centers, academic medical centers, and community-based organizations.
The University of California, San Francisco (UCSF) served as the Evaluation and Technical Assistance Provider (ETAP), offering guidance, tools, and training to sites, evaluating their work, and producing resources to help other providers replicate and scale up Rapid Start ART. This manual shares lessons learned, implementation strategies, and tools developed through the initiative. Find the summary here.
E2i: Using Evidence-Informed Interventions to Improve Health Outcomes among People Living with HIV
E2i was a four-year project where 11 evidence-informed effective interventions were tested in Ryan White HIV/AIDS Program-funded care settings and evaluated by PRC faculty and staff. The project produced multimedia toolkits to help HIV service delivery providers to adapt and implement the interventions.
Transgender Women
- TWEET (Transgender Women Engagement and Entry to Care)
- Healthy Divas
Black Men Who Have Sex With Men
Behavioral Health Integration
- Screening, Brief Intervention, and Referral to Treatment (SBIRT)
- Buprenorphine Treatment for Opioid Use Disorder in HIV Primary Care (BUP)
- Collaborative Care Management (CoCM)
Identifying and Addressing Trauma
- Trauma Informed Approach & Coordinated HIV Assistance and Navigation for Growth and Empowerment (TIA/CHANGE)
- Cognitive Processing Therapy (CPT)
- Seeking Safety
Immigrants and HIV Care
Our factsheet explores best practices for maintaining access to prevention and treatment. See the document.

FACTSHEETS. How can we identify if the information on the internet is accurate?
Created to combat internet disinformation about COVID-19. This factsheet is designed to equip individuals with a set of tools to determine falsehoods found online. English: Download here. Español: Descarga aquí.
Research and Practice with LBGTQ+ Populations
Download our document providing researchers and service providers basic information on sexual orientation and gender Identity, the LGBTQ+ community, and the health needs of LGBTQ+ people. See the document.

The OC-Light Fecal Immunochemical Test (FIT)
UCSF Prevention Research Center (PRC) researchers studied results from over 35,000 tests performed on nearly 21,000 patients. The test seems to effectively identify high-risk individuals, resulting in high-yield colonoscopy procedures. The study provides health systems with a perspective on the colonoscopy demand and performance characteristics of OC-Light as a screening tool in large, diverse patient groups. Read more here and here.
View this video in Spanish and Cantonese.
Cancer Outreach Initiative - FIT Wordless Instructions.
SPNS Latino Access Initiative
Find culturally appropriate interventions for outreach, access, and retention among Latino/a populations. These monographs describe interventions for the engagement and retention of Latinos in HIV care, including Latinos who are at high risk of living with HIV and out of care or unaware of their HIV positive status.
- Engagement in care
- Awareness of HIV status
- Improvement of health outcomes
Here are individual intervention monographs for download: https://targethiv.org/library/spns-latino-access-initiative Content developed by the evaluation and technical assistance teams of the UCSF Center for AIDS Prevention Studies (CAPS) / UCSF Prevention Research Center.
Project STYLE (Strength Through Youth Livin' Empowered)
UCSF Prevention Research Center's previous research project addresses a significant health disparity, HIV among Black and Latino gay men and men have sex with men (MSM). The STYLE+ (“Strength Through Youth Livin’ Empowered”) intervention adapts and replicates STYLE, a model intervention designed to improve the linkage of HIV-infected young MSM of color to clinical care. In collaboration with AIDS Project East Bay / APEB, the project was renamed M+ and includes the following core elements:
- Social marketing campaign
- Community outreach & HIV testing
- Red carpet HIV services
- HIV+ support services
For more information and to access the Project STYLE Adaptation Guide, Toolkit and other materials visit: https://style.ucsf.edu/


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