“Tel-Me-Box” is a small, low-cost, adherence monitoring device, developed by our team that transmits a wireless signal to a server when opened. Since it cannot assess actual drug ingestion, validation against a biological measure of adherence is crucial. The overarching hypothesis of this application is that adherence data captured by Tel-Me-Box will demonstrate strong relationships with an objective biomarker of adherence (i.e.
UCSF, the San Francisco AIDS Foundation (SFAF), and Project Inform have created an AIDS Policy Research Center (APRC) to conduct timely research to help policymakers, planning councils and community organizations address the HIV epidemic in the State of California. The center is supported with funds from the California HIV/AIDS Research Program (CHRP).
The overall goal of this study is to enhance the physical and mental health of rural Indian women living with AIDS and their children. We will achieve these goals through the use of trained village women as Accredited Social Health Activists (ASHA) to enhance the health of women and children through improved ART adherence, CD4 levels, and physical and mental health.
UCSF has a long and successful history of delivering Capacity Building Assistance (CBA) to Community-based Organizations (CBO), going back to the beginning of the epidemic. We provide information dissemination services, training, and technical assistance (TA), including the facilitation of peer-to-peer learning. Our CBA providers are also experienced at helping CBOs use social media in their prevention efforts.
The goals of the study are to reduce drug and alcohol use and recidivism among homeless female offenders (HFOs) in California. To achieve these goals, our team of UCLA and UCSF researchers plan to utilize our successful community participatory approaches to refine a gender-sensitive intervention program, Female Ex-Offender Mentoring in Care (FEM-CARE), with the help of a community advisory board.
The overall goal of this study is to improve screening, diagnoses and treatment of Common Mental Disorders among individuals with dual mental illness and cardiovascular disease diagnoses in rural South India. The multi-level intervention uses a collaborative care model that will be tested in a cluster RCT and includes low-cost, evidence-based sustainable strategies targeting multiple chronic diseases. This five-year study is being conducted in collaboration with our colleagues at St.
HIV prevalence and incidence rates have reached catastrophic levels among Young black Men who have sex with Men (YBMSM), ages 18-29. The goal of this project is to determine the efficacy of a Multilevel, theory- based Intervention, calld United Black Element (UBE), in reducing YBMSM's sexual risk behavior and increasing the frequency of HIV testing.
The Achilles heel of successful HIV treatment is adherence to antiretroviral (ARV) therapy, as non-adherence remains one of the strongest predictors of progression to AIDS and death. The recognition of the supportive role of technology for ARV adherence by the U.S. Department of Health and Human Services underscores the importance of the need for stronger evidence of the effectiveness of these interventions.
The Gay Couples Study Continuation is a five year longitudinal study that seeks to identify and examine relationship dynamics in gay couples and how those dynamics affect sexual risk behaviors with primary and outside partners. Relationship dynamics include issues such as communication style, power dynamics, interpersonal relations, and agreements around sex. Other objectives include exploring broken agreements, internal (or safety) agreements, and HIV testing rates for gay couples.
This randomized phase III trial compares topical or ablative treatment with active monitoring in preventing anal cancer in patients with human immunodeficiency virus (HIV) and high-grade squamous intraepithelial lesions (HSIL). Anal HSIL is tissue in the anal canal that has been damaged by infection with human papillomavirus (HPV) and is at risk for turning into anal cancer.
As HIV research and prevention efforts increasingly target gay men in relationships, situational factors such as couple serostatus and agreements about sex become central to examinations of risk. Discordant gay couples are of particular interest because the risk of HIV infection is seemingly near-at-hand.
The purpose of this study is to assess the feasibility and acceptability of SHEROES, a theory-driven, culturally grounded intervention to reduce sexual risk behavior among male-to-female transgender women (transwomen) at risk for HIV acquisition or transmission. HIV prevalence estimates among this population are markedly higher than estimates for other at-risk groups, and transwomen also experience severe stigma, discrimination, alienation, poverty, and victimization.
Among the numerous health disparities disproportionately burdening people of color, HIV/AIDS is Among the highest. In the African American community the HIV/AIDS epidemic is one of the most urgent public health issues. In order to address the health disparity in HIV/AIDS, detection of HIV in the African American community is crucial. the benefits for early detection of HIV include potentially prolonged duration and quality of life for those living with the virus.
UFO Presents! is a CDC-funded program aimed at the meeting the broader needs of youth and young adults with injection risk. We will provide hepatitis prevention and care education, and develop and implement programmatic materials for hepatitis C virus (HCV) counseling and education.
The overall goal of this study is to improve screening, diagnoses and treatment of Common Mental Disorders among individuals with dual mental illness and cardiovascular disease diagnoses in rural South India. The multi-level intervention uses a collaborative care model that will be tested in a cluster RCT and includes low-cost, evidence-based sustainable strategies targeting multiple chronic diseases.
This is a three-phase study to identify the specific mechanisms by which MSM stigma affect sexual risk behaviors among MSM in Beijing, China.
In Phase 1, we will explore the range of management strategies used to cope with MSM stigma via 30 in-depth qualitative interviews with MSM.
In Phase 2, we will develop, using Phase 1 qualitative data and adapting existing quantitative scales, culturally-relevant measures of explanatory constructs of interest (e.g., MSM stigma management) to establish re