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ICOHRTA Brazilian Scientists Program [summary]

This project is an extension of the International Traineeships in AIDS Prevention Studies Program (I-TAPS) through a partnership with the Centro de Estudos de AIDS do Rio Grande do Sul (CEARGS) in Porto Alegre, Brazil and with the Universidade Federale do Bahia (UFBA) in Salvador, and funded by the Fogarty International Center.

Family-Based HIV Voluntary Counseling and Testing in Patients at Risk for Tuberculosis

This study tests the efficacy of an intervention utilizing HIV rapid testing and integration of HIV Voluntary Counseling and Testing (VCT) into Tuberculosis (TB) evaluation and home-based VCT for family members, to overcome identified logistical and psychological barriers to HIV VCT among new TB patients and their family members. The specific aims of the study are: To determine the uptake of and barriers to HIV VCT among a cross-sectional sample of 2,000 TB evaluation patients offered s

IMPACT (Investigating Motivations for Participation in Anal Cancer Prevention Trials)

This project is designed to provide information that will be critical to the performance of a pivotal RCT of screening and treatment of anal intraepithelial neoplasia (AIN) to prevent anal cancer. This project will study determinants of participation in an RCT in which 50% of participants with AIN will be screened and treated, and 50% will be observed without treatment. At the end of a 5-year period, the number of anal cancer cases will be compared in both arms.

Impact of a Computer-Assisted SBIRT Program in an HIV Care Setting

Drug and alcohol use is not always addressed with patients in medical care settings, including HIV primary care settings. The screening, brief intervention, and referral to treatment (SBIRT) strategy has demonstrated an effective model to introduce screening for substance use, and standardized guidelines in a number of clinical populations, but SBIRT for drug and alcohol use has not been tested in an HIV primary care setting.

International Travel Research to Inform Prevention (I-TRIP)

I-TRIP studies sexual risk behavior in the context of international travel among gay and bisexual men from the San Francisco Bay Area. The specific aims are: To measure the prevalence of sexual risk behavior during international travel among gay and bisexual men from the Bay Area. To document the prevalence of ART drug resistance among gay and bisexual international travelers from the Bay Area.

HIV Prevention among Township Men Who Have Sex with Men in South Africa

This project has two aims: 1 To describe collective and individual belief systems of low-income township men who have sex with men (MSM) related to their sexuality, sexual health, choice of sexual partners, use of drugs and alcohol, use of condoms, utilization of health services, HIV voluntary counseling and testing (VCT) and disclosure of HIV status, in order to describe prevailing cultural norms around these subjects’ behaviors To assess the prevalence of HIV risk factors an

Intervention Development for Re-Engagement in Care

This research complements improvements in HIV services being developed in San Francisco under the auspices of the CDC’s Enhanced Comprehensive HIV Prevention Planning (ECHPP), and augments ECHPP-related evaluations already being supported through the NIH-supported Centers for AIDS Research.

Assessment of Economic Factors Associated with the Psychological Well-Being of HIV+ Persons in Kenya

The specific aim of this study is to conduct a preliminary assessment of the association between measures of economic context and material well-being on the one hand, and positive and negative psychological wellbeing on the other.

A Pilot RCT of Expressive Writing with HIV-Positive Methamphetamine Users

It is well established that HIV-positive persons who use stimulants such as methamphetamine are at increased risk for transmitting medication-resistant strains HIV. Mental health co-morbidities such as symptoms of post-traumatic stress disorder and HIV-specific traumatic stress may substantially contribute to increased stimulant use among HIV-positive persons.

Archival Analysis of the Urban Men’s Health Study 2002

This study will utilize data from the Urban Men’s Health Study 2002, a probability-based survey of 879 men who have sex with men (MSM) in San Francisco. These data provide a unique, cost-effective opportunity to examine psychological correlates of stimulant use among MSM who were recruited through probability-based sampling methods.

ASHA Improving Health and Nutrition of Indian Women with AIDS and their Children

The overall goal of this study is to enhance the physical and mental health of rural Indian women living with AIDS and their children. We will achieve these goals through the use of trained village women as Accredited Social Health Activists (ASHA) to enhance the health of women and children through improved ART adherence, CD4 levels, and physical and mental health.

Assessing the Feasibility of Conducting a Randomized Community Trial of the Encontros Intervention Model among Sex Workers in Brazil (Lippman, S)

This study will determine the feasibility of conducting a CRCT of a promising multi-component intervention among sex workers in Brazil. Determining study feasibility includes documenting local interest and input from key stakeholders and carrying out an analysis of costs to implement a large intervention trial.

Assessment of Economic Factors Associated with the Psychological Well-Being of HIV+ Persons in Kenya

The specific aim of this study is to conduct a preliminary assessment of the association between measures of economic context and material well-being on the one hand, and positive and negative psychological well-being on the other.

Barriers to and Retention in Support Services among HIV+ Transwomen

The purpose of this study is to examine barriers to and retention in support services among HIV+ transwomen (women who were assigned a male sex at birth) and to explore the challenges and potential benefits of integrating HIV+ transwomen into services for HIV+ non-transgender women. This study will collect qualitative data with 14 HIV+ transwomen and 10 support services providers in Alameda County, CA.

Barriers to and Retention in Support Services among HIV+ Transwomen

The purpose of this study is to examine barriers to and retention in support services among HIV+ transwomen (women who were assigned a male sex at birth) and to explore the challenges and potential benefits of integrating HIV+ transwomen into services for HIV+ non-transgender women. This study will collect qualitative data with 14 HIV+ transwomen and 10 support services providers in Alameda County, CA.

Characterizing the Social Environment for STI Testing and Treatment for Young, Minority Men in San Francisco

This project characterizes the STI testing and treatment environment for young, African American men in San Francisco, CA, by exploring STI services use, barriers to care, and preferences for future diagnostic technologies and testing strategies. This cross sectional study is conducted among 100 men aged 15-24 using a street intercept survey in predominantly minority, low income neighborhoods in San Francisco.

Disclosure Intervention for Zimbabwean Parents

We propose a randomized controlled trial of a disclosure intervention in which 300 PLH are randomized to either an: 1) experimental condition, a disclosure intervention (n = 150 parents) or 2) attention control condition, a nutrition intervention (n = 150). The intervention's impact will be assessed over two years (recruitment, 3, 6, 12, 18, & 24 months).

Disclosure Intervention for Zimbabwean Parents

We propose a randomized controlled trial of a disclosure intervention in which 300 PLH are randomized to either an: 1) experimental condition, a disclosure intervention (n = 150 parents) or 2) attention control condition, a nutrition intervention (n = 150). The intervention's impact will be assessed over two years (recruitment, 3, 6, 12, 18, & 24 months).

Duo Project: Relationship Factors and HIV Treatment Adherence

The DUO Project investigates how relationship factors are associated with adherence to antiretroviral therapy (ART). Based on recruitment feasibility and the epidemiology of the HIV epidemic in the San Francisco area, HIV+ seroconcordant and serodiscordant male couples are included in the study’s three phases: Phase 1. We conducted a qualitative investigation of relationship dynamics and partner tactics related to HIV medication adherence. Phase 2.

Dyadic Processes in the Patient-Provider Relationship

The purpose of this project is to (1) provide expanded mentoring of early career clinician- researchers in patient oriented research (POR), and (2) extend his current research program to the study of patient-provider dyads, which will be studied through the integration of research tools into electronic health records (EHR) systems. Dr. Johnson's trainees have emerged as research clinicians interested in conducting POR.