UCSF is one site of an NIMH-funded multi-site, international efficacy trial of a behavioral intervention to reduce the incidence of HIV infection. Collaborating international sites teamed with US sites are: Zimbabwe (S. Morin, UCSF PI), South Africa (T. Coates, UCLA PI), Tanzania (M. Sweat, Johns Hopkins University PI) and Thailand (D. Celantano, Johns Hopkins University PI). In this prevention trial, 34 communities in Africa (Tanzania, Zimbabwe, and South Africa) and 14 communities in Thailand will be randomized to either a community-based HIV voluntary counseling and testing (CBVCT) intervention or clinic-based standard VCT (SVCT).
The intervention has three major strategies:
- To make VCT more available in community settings
- To engage the community through outreach and community mobilization
- To provide post-test support services
These strategies are designed to change community norms and reduce risk for HIV among all community members, irrespective of whether they participated directly in the intervention. Thus, we plan a community-level sampling approach as opposed to a cohort design to evaluate outcomes.